ARTIFICIAL SALIVA AND ITS FUNCTIONAL CONTRIBUTION TO ORAL PROSTHETICS IN XEROSTOMIC PATIENTS: A REVIEW

Kamel Earar, Emil Ceban, Doriana Agop Forna, Sondos Al Hamadneh, Sonia-Teodora Statescu-Manaila, Caterina Nela Dumitru, Mariana Lupoae

DOI: 10.62610/RJOR.2025.2.17.52

Abstract

Xerostomia, or dry mouth, is a common condition that significantly affects oral function, comfort, and prosthetic rehabilitation, particularly in elderly and medically compromised patients. Saliva plays a vital role in denture retention, mucosal protection, and overall oral health. In cases of irreversible salivary gland hypofunction, artificial saliva serves as a non-invasive, palliative solution aimed at restoring lubrication and improving the quality of life. This review explores the physiological roles of saliva, the clinical implications of its deficiency, and the functional contribution of artificial saliva in prosthodontic treatment. It discusses the composition and classification of artificial saliva products, their mechanism of action, and practical applications in oral prosthetics. Evidence suggests that artificial saliva enhances denture comfort, retention, and patient satisfaction, although its effects are temporary and vary across formulations. Limitations include frequent reapplication, lack of antimicrobial or remineralizing properties, and patient-specific variability in acceptance. The review also highlights future directions, such as biomimetic formulations, nanotechnology-based systems, and smart prosthetics designed for controlled saliva release. In conclusion, artificial saliva remains a key adjunct in managing xerostomia, and its strategic use supports functional and comfortable prosthetic rehabilitation in affected individuals.