Mădălina Borcă, Alexandru Borcă, Laura Romila, Alin Ciobica, Ioannis Mavroudis, Mihoko Tomida, Alin Iordache, Antoneta Dacia Petroaie, Norina Forna
ABSTRACT
The correlation between the high incidence of oro-dental pathologies (periodontitis, oral cancer) and the increased level of ROS in the human body have led to the need to use alternative treatments, namely to the use of active principles from medicinal plants that have a considerable antioxidant effect, thus reducing the risk of producing these oro-dental pathologies. In this sense, some of the bioactive compounds present in medicinal plants such as turmeric acid extracted from Curcuma longa, polyphenolic compounds extracted from Camellia sinensis, apigenin extracted from Moringa oleifera, timolol extracted from Thymus vulgaris, etc. are already used in oral care products, giving consumers the opportunity to capitalize on the therapeutic properties of natural plant extracts. Although many medicinal plants exhibit remarkable antioxidant properties, observed in vitro studies, when switching to in vivo studies these antioxidant properties are no longer similar due to interference between physiopharmacological processes such as absorption, metabolism, excretion. Therefore, additional studies are needed to prove even more clearly the antioxidant capacities of medicinal plants and implicitly their applicability in the prevention of oro-dental pathologies.
DOI : 10.6261/RJOR.2024.2.16.28
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