Acatrinei Doneta, Forna Norina, Diaconu Irina, Rosoiu Natalia
Abstract
- Periodontal disease is a group of inflammatory oral infections initiated by oral pathogens that exist as a complex biofilm on the surface of the teeth and can cause destruction of the teeth and supporting tissues.
- The severity of these diseases varies from the medium and reversible inflammation of the gum, the gingivitis to the chronic destruction of the tissues related to the formation of periodontal bags resulting in the loss of teeth.
- More than 500 bacterial species have been identified in the subgingival human plaque, including Porphyromonas gingivalis, a gram-negative bacterium that is the major etiological agent contributing to the development of chronic parodontopathy.
- This bacterium produces virulent factors that cause periodontal tissue destruction directly or indirectly through the host’s inflammatory response.
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