Romanian Journal of Oral Rehabilitation Numarul 3 VOLUMETRIC EVALUATION OF BONE GRAFT IN GUIDED BONE REGENERATION USING P4HB MESH AND TITANIUM MESH. COMPARATIVE STUDY

VOLUMETRIC EVALUATION OF BONE GRAFT IN GUIDED BONE REGENERATION USING P4HB MESH AND TITANIUM MESH. COMPARATIVE STUDY

Zugrav Vasile, Chele Nicolae, Chele Dumitru, Norina Consuela Forna, Doriana Agop Forna, Motelica Gabriela, Dabija Ion, Mostovei Andrei

ABSTRACT

Aim of the study The aim of the present study was to compare the stability of bone graft volume in guided bone regeneration procedures in patients with alveolar process atrophy who were treated using titanium mesh and resorbable polymeric mesh made of poly-4-hydroxybutyrate (P4HB). Materials and methods A randomized clinical study was conducted on 70 patients, divided into two groups. The study group consisted of 35 patients treated with guided bone regeneration surgery using resorbable P4HB mesh, while the control group comprised 35 patients with similar pathologies who underwent guided bone regeneration using a titanium membrane. A CT scan was performed 2-3 weeks after the initial procedure to calculate the added/augmented graft volume (VGA-added/initial) using Slider 3D software. The second surgical stage was performed at least 8 months later, which included a CT scan to measure the volume of regenerated bone tissue (VON) using the same software. Data were analyzed using the R Studio software (Version 2024.04.1+748). Results The study found that the volume of the augmented graft did not undergo significant changes during the regeneration period in either group, with volumetric values showing a close correlation throughout the same period. Conclusions The polymeric mesh made of P4HB provides three-dimensional stability to the bone graft during healing, comparable to that of titanium mesh.

DOI : 10.62610/RJOR.2025.3.17.31

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