Ioan Sarbu, Norina Consuela Forna, Doriana Agop Forna, Marius Vacaru-Carnaru, Cristi Budacu
DOI : 10.62610/RJOR.2025.2.17.35
Abstract
Modern dental implantology is based on a complex correlation between surgical procedures, postoperative inflammatory response, and the administration of anti-inflammatory drugs. Local inflammation is an essential physiological process in initiating healing and osseointegration, however, in excessive forms, it can compromise the stability of the implant and the patient’s comfort. In this context, NSAIDs and corticosteroids are commonly used to reduce pain and edema, but their effects on the bone regeneration process are controversial. The review looks at the influence of these drugs depending on the type of surgery, the time of administration, and the systemic condition of the patient. The risks of exaggerated inhibition of inflammation are highlighted, as well as the importance of a personalized approach, adapted to each clinical case. It also discusses the prospects for future research, including the use of biomaterials with local anti-inflammatory effects and the application of the principles of personalized medicine. The conclusion emphasizes the need for an integrated vision, which harmonizes surgery, pharmacology, and tissue biology to obtain functional and stable long-term results in dental implantology.