Marius Cristian Mârțu, Alexandru Stingheriu, Oana Aștefanei, Iustin Iațentiuc, Ioana Mârțu, Oana Bitere-Popa
DOI : 10.62610/RJOR.2024.4.16.59
Abstract
Cholesteatoma of the middle ear is a chronic inflammatory condition characterized by the presence, formation, or migration of epithelial cells into the mucosal region of the middle ear. This results in the progressive development of a matrix-like sac filled with keratinized debris arranged in concentric layers. Clinically, it typically presents with symptoms such as hearing loss, a sensation of ear fullness, and occasionally otorrhea (auricular suppuration).
Advancements in modern diagnostic tools have facilitated early detection, while the widespread use of antibiotics has significantly reduced the incidence of complications. However, these advances have also contributed to the emergence of pathogens with heightened virulence and resistance to antibiotics, posing new therapeutic challenges.
Furthermore, due to the increase in life expectancy and improved access to quality medical services as well as the enhancement of medical performance, there has been an increase in the number of elderly individuals and those with compromised immunity. This has led to the development of opportunistic infections and the emergence of patients with atypical (masked) symptoms. These factors keep cholesteatoma complications in mind.