Stefana Maria Moisa, Ancuta Lupu, Vasile Valeriu Lupu, Leonard Pertea, Ingrith Miron
ABSTRACT
Impressive steps have been made since 1955, when the first guideline on infective endocarditis prophylaxis was issued, until the present days. If in the past prophylaxis was begun 2 days before the procedure and continued for 2 more days after the intervention, a single dose is now recommended in the present. National Institute for Health and Care Excellence in the United Kingdom recommends no prophylaxis, but some claim an increase in infective endocarditis has been demonstrated following this recommendation.