Alina Mihaela Calin, Aurel Nechita, Ana Magdalena Bratu, Ciprian Adrian Dinu, Iulia Alecsandra Salcianu, Gabi Topor, Victorita Stefanescu, Cristian Guțu, Elena Roxana Bogdan Goroftei, Simona Parvu, Mioara Decuseară, Iulian Catalin Bratu
Abstract
This review aims to evaluate efficacy and drug treatment options in cases of vaginal and vulvar candidiasis associated with diabetes. We conducted an exhaustive literature review, looking at relevant clinical trials, meta-analyses, and clinical experiences. Patients with candidiasis and diabetes mellitus were included in a clinical case study to assess their response to treatment. Antifungals such as fluconazole and clotrimazole have been effective in treating candidiasis, but success has been influenced by glucose control levels. Proper diabetes management, along with antifungal therapy, resulted in decreased recurrences. Treatment of candidiasis in a diabetic context requires an integrated approach, including antifungal therapy and adequate management of diabetes. Strict blood glucose control plays a crucial role in preventing recurrences and improving the quality of life of affected patients. Further studies are needed to better understand the complex interactions between diabetes and candidiasis, paving the way for the development of more personalized and effective treatment strategies.
DOI : 10.6261/RJOR.2024.1.16.57
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